Education： 2000.9-2004.6, Veterinary medicine, Hebei Agricultural University, Bachelor's degree
2004.9-2009.6，Preventive Veterinary Medicine, Huazhong Agricultural University, Ph.D Professional Experience： 2018.10--- Jiangsu University, School of food and Biological Engineering, M.Sc Supervisor
2018.10--- Jiangsu Academy of Agricultural Sciences, Professor
2015.9-2016.9 Stanford University, Visiting scholar
2012.12--- Nanjing Agricultural University, M.Sc Supervisor
2012.8-2018.10 Jiangsu Academy of Agricultural Sciences, Associate Professor Scientific Research Field： (1) Biotechnology, Pathogen diagnosis methods;
(2) Development of veterinary microbial vaccine and pathogenic mechanism;
(3) Research on the prevention and control technology of pig viral diarrhea;
(4) Development of adjuvants and antigen delivery systems. Social academic post and honor： Reviewer: Sci Rep、Vet Microbiol、Arch Virol、PLoS ONE、J Virol Methods、Medicine、Protein & Peptide Letters Teaching Courses： Published papers： 1. Ren L*, Ding S*#, Song Y*, Li B*, Co J, Ramanathan M, Amieva MR, Khavari PA, and Greenberg HB#. Profiling of rotavirus 3’ UTR binding proteins reveals ATP synthase subunit ATP5B as a novel host factor that supports late stage virus replication. J Biol. Chem. 2019, In Press.
2. Du L, Yu Z, Pang F, Xu X, Mao A, Yuan W, He K, Li B*. Targeted Delivery of GP5 Antigen of PRRSV to M Cells Enhances the Antigen-Specific Systemic and Mucosal Immune Responses. Front Cell Infect Microbiol. 2018, 25;8:7. doi: 10.3389/fcimb.
3. Bin Li, Luping Du, Zhengyu Yu, Bing Sun, Xiangwei Xu, Baochao Fan, Rongli Guo, Wanzhe Yuan, Kongwang He. Poly (D, L-lactide-co-glycolide) nanoparticle-entrapped vaccine induces a protective immune response against porcine epidemic diarrhea virus infection in piglets. Vaccine, 2017.15;35(50):7010-7017.
4. Bin Li, Siyuan Ding, Ningguo Feng, Nancie Mooney, Yaw Shin Ooi, Lili Ren, Jonathan Diep, Marcus R. Kelly, Linda L. Yasukawa, John T. Patton, Hiroyuki Yamazaki, Tomoaki Shirao, Peter K. Jackson, and Harry B. Greenberg*. Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis. Proc Natl Acad Sci USA. 2017. 114(18):E3642-E3651.
5. Lin H, Li B, Chen L, Ma Z, He K, Fan H. Differential Protein Analysis of IPEC-J2 Cells Infected with Porcine Epidemic Diarrhea Virus Pandemic and Classical Strains Elucidates the Pathogenesis of Infection. J Proteome Res. 2017, 16(6):2113-2120.
6. Fan B, Jiao D, Zhao X, Pang F, Xiao Q, Yu Z, Mao A, Guo R, Yuan W, Zhao P, He K, Li B*. Characterization of Chinese Porcine Epidemic Diarrhea Virus with Novel Insertions and Deletions in Genome. Sci Rep. 2017, 7:44209.
7. Du L, Pang F, Yu Z, Xu X, Fan B, Huang K, He K, Li B*. Assessment of the efficacy of two novel DNA vaccine formulations against highly pathogenic Porcine Reproductive and Respiratory Syndrome Virus. Sci Rep. 2017, 7: 41886;
8. Luping Du, Bin Li, Fengjiao Pang, Zhengyu Yu, Xiangwei Xu, Baochao Fan, Yeping Tan, Kongwang He, Kehe Huang. Porcine GPX1 enhances GP5-based DNA vaccination against porcine reproductive and respiratory syndrome virus. Veterinary Immunology and Immunopathology, 2017, 183, 31-39.
9. Fan B, Yu Z, Pang F, Xu X, Zhang B, Guo R, He K, Li B*. Characterization of a pathogenic full-length cDNA clone of a virulent porcine epidemic diarrhea virus strain AH2012/12 in China. Virology. 2017 500, 50-61.
10. Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, Greenberg HB. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. PLoS Pathog. 2016, 5;12(10):e1005929.
11. Du L1, Bin Li (co-first author), Xu X, Sun B, Pang F, Wen L, Huang K, He K. Adsorption of a porcine reproductive and respiratory syndrome virus DNA vaccine candidate onto biodegradable nanoparticles improves immunogenicity in mice. Arch Virol. 2015, 160(6):1543-7.
12. Bin Li, Luping Du, Xiangwei Xu, Bing Sun, Zhengyu Yu, Zhixin Feng, Maojun Liu, Yanna Wei, Haiyan Wang, Guoqing Shao, Kongwang He.Transcription analysis on response of porcine alveolar macrophages to co-infection of the highly pathogenic porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae. Virus research, 2015, 196,60-69.
13. Bin Li, Luping Du, Bing Sun, Zhengyu Yu, Maojun Liu, Zhixin Feng, Yanna Wei, Haiyan Wang, Guoqing Shao, Kongwang He. Transcription Analysis of the Porcine Alveolar MacrophageResponse to Mycoplasma hyopneumoniae. PLoS ONE 2014, 9(8): e101968.
14. Luping Du, Bin Li (co-first author), Kongwang He, Haibin Zhang, Kehe Huang and Shaobo Xiao. Construction and Immunogenicity of DNA Vaccines Encoding Fusion Protein of Porcine IFN-1 and GP5 Gene of Porcine Reproductive and Respiratory Syndrome Virus. BioMed Research International, Volume 2013 (2013), Article ID 318698.
15. Bin Li*, Du L, Sun B, Yu Z, Wen L, Zhang X, Guo R, Ni Y, Hu Y, Zhou J, Zhu H, Lv L, Yu Y, Wang X, He K*. Monoclonal antibodies against Nsp2 protein of the highly pathogenic porcine reproductive and respiratory syndrome virus. Monoclon Antib Immunodiagn Immunother. 2013, 32(5): 362-365.
16. Bin Li*, Bing Sun, Lu-ping Du, Ai-hua Mao, Li-bin Wen, Yan-xiu Ni, Xue-han Zhang, Kong-wang He*. Development of a loop-mediated isothermal amplification assay for the detection of porcine hokovirus. J Virol Methods. 2013, 193(2): 415-418.
17. Bin Li*, Haofei Liu, Kongwang He, Rongli Guo, Yanxiu Ni, Luping Du, Libin Wen, Xuehan Zhang, Zhengyu Yu, Junming Zhou,Aihua Mao, Lixin Lv, Yiyi Hu, Yang Yu, Haodan Zhu, Xiaomin Wang. Complete genome sequence of a recombinant porcine epidemic diarrhea virus strain from eastern China. Genome Announc. 2013, 18;1(2): e00105-13.
18. Jianbo Cao, Bin Li (co-first author), Liurong Fang, Huanchun Chen, Shaobo Xiao. Pathogenesis of nonsuppurative encephalitis caused by highly pathogenic Porcine reproductive and respiratory syndrome virus. J Vet Diagn Invest. 2012, 24(4):767-71.
19. Bin Li*, Ma Junjie, Liu Yanling, Wen Libin, Yu Zhengyu, Ni Yanxiu, Zhang Xuehan, Zhou Junming, Guo Rongli, Wang Xiaomin, Feng Zhixin, Hu Yiyi, Lv Lixin, He Kongwang. Complete genome sequence of a highly prevalent porcine circovirus 2 isolated from piglet stool samples in China，J. Virol, 2012, 86(8), 4716.
20. Bin Li, Ma JJ, Xiao SB, Fang LR, Zeng SL, Wen LB, Zhang XH, Ni YX, Guo RL, Yu ZY, Zhou JM, Mao AH, Lv LX, Wang XM, He KW. Complete genome sequence of a novel species of porcine bocavirus, PBoV5. J. Virol. 2012, 86(2):1286–1287.
21. Bin Li, Ma JJ, Xiao SB, Wen LB, Ni YX, Zhang XH, Fang LR, He KW. Genome sequence of a highly prevalent porcine partetravirus in mainland China. J. Virol. 2012, 86:1899.
22. Bin Li, Ma JJ, Xiao SB, Zhang XH, Wen LB, Mao L, Ni YX, Guo RL, Zhou JM, Lv LX, He KW. Development of a loop-mediated isothermal amplification method for rapid detection of porcine boca-like virus. J. Virol. Methods. 2012, 179:390-395.
23. Bin Li, Liurong Fang, Xueliang Guo, Janfeng Gao, Tao Song, Jing Bi, Kongwang He, Huanchun, Chen, Shaobo Xiao. Epidemiology and Evolutionary Characteristics of the Porcine Reproductive and Respiratory Syndrome Virus in China between 2006 and 2010. J Clin Microbiol. 2011, 49 (9): 3175-3183.
24. Bin Li, Xiao SB, Ma JJ, Liu YL, Mao L, Wen LB, Mao AH, Zhang XH, Ni YX, Guo RL, Zhou JM, Yu ZY, Lv LX, Wang XM, Fang LR, Chen HC, He KW. Development of a novel TaqMan-based real-time PCR assay for the detection of porcine boca-like virus (Pbo-likeV). Virol. J. 2011, 8:357.
25. Bin Li, Liurong Fang, Suyan Liu, Fuwei Zhao, Yunbo Jiang, Kongwang He, Huanchun Chen, Shaobo Xiao The genomic diversity of Chinese porcine reproductive and respiratory syndrome virus isolates from 1996 to 2009. Vet Microbiol. 2010, 146: 226-237.
26. Bin Li, Liurong Fang, Zuofei Xu, Suyan Liu, Jianfeng Gao, Yunbo Jiang, Huanchun Chen, Shaobo Xiao. Recombination in vaccine and circulating strains of porcine reproductive and respiratory syndrome virus. Emerg Infect Dis. 2009, 15 (12): 2032-2035.
27. Bin Li, Shaobo Xiao, Yanwei Wang, Shanshan Xu, Yunbo Jiang, Huanchun Chen, Liurong Fang. Immunogenicity of the highly pathogenic porcine reproductive and respiratory syndrome virus GP5 protein encoded by a synthetic ORF5 gene. Vaccine. 2009, 27: 1957-1963. Main Scientific Research Projects： 2019-2022 Natural Science Foundation of China (31872481)；
2017-2020 National Key Research and Development Program of China （2018YFD0500101）
2016-2020 National Key Research and Development Program of China（2016YFD0500101）
2015-2018 Natural Science Foundation of China (31472204)；
2013-2016 The Innovation of Agricultural Science and Technology of Jiangsu Province (CX(13)3069):
2011-2013 Natural Science Foundation of China (31001066)； Patents： Scientific Research Achievements and Awards Number of postgraduates under supervision 3 Number of supervised masters and Ph.D. 8 Number of supervised undergraduates 10 The above information updated Apr. 2019 |
