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Guoqing Shao


NameGuoqing Shao

Technical postProfessor

AddressNo.50 Zhongling Street, Xuanwu District, Jiansu Academy of   Agricultural Sciences Nanjing, 210014,PR. China

E-mailgqshaonj@163.com

Education

2005.2-2005.8      Guelph University, Canada -- Advanced Visiting Scholar

1995.6-1998.6      Nanjing Agricultural University, China (Ph.D) in Prevention   Veterinary Medicine

1985.6-1988.6      Nanjing Agricultural University, China (M.Sc) in Animal   Infectious Diseases

1980.6-1985.6      Nanjing Agricultural University, China (M.Sc) in Veterinary   Medicine

Professional   Experience

2013/9-   Current   Professor  

              Institute of Veterinary Medicine,

              Jiangsu Academy of Agricultural Sciences   (JAAS), Chinas

Scientific Research Field

Immune   mechanisms and immune techniques of swine mycoplasma pneumonia

Social academic post and honor

1.Member of   the Scientific Committee of the 17th International Organization of Mycoplasma   (IOM) Congress (http://www.17thiomcongress.com/)

2.As the 8th   President of Asian Organization for Mycoplasmology (2018-2020)

3.Member of   National Committee of China Agriculture Department for Animal Epidemic   Disease Control (2012-now)

4.Member of   National Committee of China Veterinary Drug Evaluation, Ministry of   Agriculture (2017-2021)

Teaching Courses

Published   papers

1.H. Wang, Z.   Feng, Y. Wu, Y. Wei, Y. Gan, L. Hua, B. Li, X. Wang, M. Liu, Q. Xiong, and G.   Shao, 'The Effects of Mycoplasma Hyopneumoniae on Porcine Circovirus Type 2   Replication in Vitro Pk-15 Cells', Res Vet Sci, 105 (2016), 56-61.

2.Q. Xiong, J.   Wang, Y. Ji, B. Ni, B. Zhang, Q. Ma, Y. Wei, S. Xiao, Z. Feng, M. Liu, and G.   Shao, 'The Functions of the Variable Lipoprotein Family of Mycoplasma   Hyorhinis in Adherence to Host Cells', Vet Microbiol, 186 (2016), 82-9.

3.Q. Xiong, B.   Zhang, J. Wang, B. Ni, Y. Ji, Y. Wei, S. Xiao, Z. Feng, M. Liu, and G. Shao,   'Characterization of the Role in Adherence of Mycoplasma Hyorhinis Variable   Lipoproteins Containing Different Repeat Unit Copy Numbers', Vet Microbiol,   197 (2016), 39-46.

4.Bai F, Ni B,   Liu M, Feng Z, Xiong Q, Shao G. Mycoplasma hyopneumoniae-derived   lipid-associated membrane proteins induce inflammation and apoptosis in   porcine peripheral blood mononuclear cells in vitro. Vet Microbiol. 2015,   175(1):58-67.

5.Xiong Q, Wei   Y, Feng Z, Gan Y, Liu Z, Liu M, Bai F, Shao G. Protective efficacy of a live   attenuated Mycoplasma hyopneumoniae vaccine with an ISCOM-matrix adjuvant in   pigs. Vet J. 2014.99(2):268-74.

6.Xiong Q, Wei   Y, Xie H, Feng Z, Gan Y, Wang C, Liu M, Bai F, Xie F, Shao G. Effect of   different adjuvant formulations on the immunogenicity and protective effect   of a liveMycoplasma hyopneumoniae vaccine after intramuscular inoculation.   Vaccine. 2014.32(27):3445-51.

7.Hua LZ, Wu   YZ, Bai FF, William KK, Feng ZX, Liu MJ, Yao JT, Zhang X, Shao GQ.   Comparative analysis of mucosal immunity to Mycoplasma hyopneumoniae in   Jiangquhai porcine lean strain and DLY piglets. Genet Mol Res.   2014.13(3):5199-206.

8.Feng ZX, Bai   Y, Yao JT, Pharr GT, Wan XF, Xiao SB, Chi LZ, Gan Y, Wang HY, Wei YN, Liu MJ,   Xiong QY, Bai FF, Li B, Wu XS, Shao GQ. Use of serological and mucosal immune   responses to Mycoplasma hyopneumoniae antigens P97R1, P46 and P36 in the   diagnosis of infection. Vet J. 2014 Jul 1. pii: S1090-0233(14)00276-7. doi:   10.1016/j.tvjl.2014.06.019.

9.Xiong Q, Wei   Y, Feng Z, Gan Y, Liu Z, Liu M, Bai F, Shao G. Protective efficacy of a live   attenuated Mycoplasma hyopneumoniae vaccine with an ISCOM-matrix adjuvant in   pigs. Vet J. 2014.99(2):268-74.

10.Xiong Q,   Wei Y, Xie H, Feng Z, Gan Y, Wang C, Liu M, Bai F, Xie F, Shao G. Effect of   different adjuvant formulations on the immunogenicity and protective effect   of a liveMycoplasma hyopneumoniae vaccine after intramuscular inoculation.   Vaccine. 2014.32(27):3445-51.

11.Bai F, Ni   B,Liu M, Feng Z, Xiong Q, Xiao S,Shao G.Mycoplasma hyopneumoniae-derived   lipid-associated membrane proteins induce apoptosis in porcine alveolar   macrophage via increasing nitric oxide production, oxidative stress, and   caspase-3 activation. Vet Immunol Immunopathol. 2013.155(3):155-61.

Main Scientific Research Projects

1. Sub-project   of national key research and development program, development of special   laboratory animal for prevention and control of livestock and poultry   diseases, sub-subject: establishment and evaluation of SPF pig disease model,   201707-202012

2. Sub-project   of national key research and development program, research on rapid detection   technology of swine important epidemic diseases, sub-subject: antibody   detection technology of Mycoplasma pneumonia, 201607-202012

Patents

Core patent

1.An   attenuated Mycoplasma hyopneumoniae strains (ZL99114276.4)

2.PCT-ATTENUATED   LIVE VACCINE AGAINST MYCOPLASMAL PNEUMONIA OF SWINE (MPS) AND USE   THEREOF-(US9849168B2)

Ordinary   patents

3.Recombination   Mycoplasma hyopneumoniae P97R1 expressed in Pichia (ZL200910027159.1)

4.Gene   Recombination of P36 Pichia and Protein Expression of MPS (ZL200910027160.4)

5.Preparation   and the application of vaccine adjuvant to live attenuated vaccine of swine   mycoplasma pneumonia (ZL201010288021.X)

6.Preparation   and the application of vaccine adjuvant to live attenuated vaccine of   Mycoplasma hyopneumoniae  (ZL201010288025.8)

7.Preparation   of LAMP diagnostic kit for Mycoplasma hyopneumoniae (ZL201110033271.3)

8.The   detection of Mycoplasma hyorhinis by nested PCR (ZL201210115339.7)

9.Preparation   and application of a LAMP diagnostic kit for Mycoplasma hyorhinis   (ZL201210170783.9)

10.The ELISA   kit of multi-recombinant antigens against Mycoplasma hyopneumoniae   (ZL201210244908.8)

11.The preparation   and detection of an aerosol live vaccine of Mycoplasma hyopneumoniae   (ZL201210275639.1)

12.Primer and   probe for Mycoplasma hyorhinis detection by real-time fluorescence   quantitative reverse transcription-PCR (ZL201210296912.9)

13.The   diagnostic kit of Mycoplasma hyopneumoniae antigen and its preparation   (ZL201210429480.4)

14.A   quantitatived gathering unit for aerosol vaccine (ZL201220357811.3)

15.A sampler   for aerosols of Mycoplasma hyopneumoniae  (ZL201220435911.3)

16.Preparation   of special diluent for swine mycoplasma pneumonia vaccine (ZL201310017232.3)

17.The   application of a Mycoplasma hyopneumoniae vaccine strain (ZL201310605986.0)

18.A   Mycoplasma hyopneumoniae vaccine strain (ZL201310608564.9)

19.A sampler   for Trachea lavage fluid of animal (ZL201320497672.9)

20.An   implement for transporting SPF pig (ZL201320734879.3)

Scientific Research Achievements and Awards

1.National   Award for Technological Invention (2015), won the second prize. Issued by the   State Council of the People's Republic of China. Project Title: Development   and application of a safe and efficient attenuated vaccine of Mycoplasma   hyopneumoniae.

2.Chinese   patent award of excellence (2015). Issued by the State Intellectual Property   Office of the People's Republic of China. Patent title: The Cloning of   Attenuated Strain of Mycoplasma hyopneumoniae.

3.In 2011 in   Beijing, China “The Integrated Applications of the Development and   Comprehensive Prevention and Control Technology of Swine Mycoplasma   hyopneumoniae Vaccine," won the first prize of "China Agricultural   Science and Technology award", issued by China Agricultural Society   Awards Committee and Ministry of Agriculture, P.R. China.

4.In 2011 in   Hangzhou, China "Swine Live Attenuated Vaccine of Mycoplasma   hyopneumoniae (168 strain)" won the "Fifth China Technology Market   Association Golden Bridge Award" presented by China Technology Market   Association.

Number of   postgraduates under supervision

M.Sc 1Ph.D 4Post-doctoral 1

Number of   supervised masters and Ph.D.

2016-2018 M.Sc 10Ph.D 1Post-doctoral 3

Number of   supervised undergraduates

The above   information updated

Apr.2021



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