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硕士生导师 - 闫景坤 详细信息
  个人简介
姓名 闫景坤
性别
出生日期 1980年11月
职称 副教授
电话 15952819661
传真
Email jkyan_27@163.com
       详细介绍

【学术简介】


学习经历:

20009-20046月,河南工业大学,食品科学与工程专业,学士学位。

20049-20076月,河南工业大学,粮食油脂与植物蛋白工程专业,硕士学位。

20079-20106月,华南理工大学,制糖工程专业,博士学位。

教学及研究经历:

20107-至今,江苏大学食品与生物工程学院教师。

20124-20159月,江苏大学食品科学与工程博士后

201310-20142月,香港理工大学应用生物及化学科技学系,访问学者(Research Associate)。

201512-201612月,香港中文大学生命科学院,访问学者(Research Associate)。

学术社会兼职及荣誉:

20148-20158月,江苏省第七批科技镇长团,泗洪县第二批科技镇长团副团长,挂职泗洪县科技局副局长。


【主讲课程】

硕士研究生:

本科生:生物化学、食品工厂设计、食品质量与安全学


【指导硕、博士生研究方向】

硕士研究生:

1)生物大分子多糖的分离纯化、结构表征、活性及其应用;

2)生物大分子多糖的相互作用、功能化改性及其应用;

3)食品功能性低聚糖的开发及其应用。

 

【研究领域】

1. 活性多糖的制备、结构、活性及构效关系;

2. 生物大分子多糖的相互作用、功能化修饰、活性及应用;

3. 农产品新资源(功能低聚糖)的开发及应用。


【主要论著】

近年来,以第一作者或通讯作者在国内外学术刊物Critical Reviews in Food Science & NutritionJournal of Functional FoodsFood ChemitryCarbohydrate Polymers等杂志发表学术论文50篇,其中SCI论文36篇,影响因子3以上28篇,国际期刊Journal of Functional FoodsCarbohydrate PolymersFood ChemistryUltrasonics SonochemistryFood & Function, International Journal of Biological MacromoleculesProcess BiochemistrySeparation and Purification Technology的审稿人,Book chapter1篇。参编中国科学院食品科学与工程专业系列“十二五”规划教材《功能性食品学》和《食品化学》2部。

² 代表性论文(著)(“*”为通讯作者):

2018

1. Yan, J.K*., Wang, Y.Y., Qiu, W.Y., Ma, H., Wang, Z.B. (2018). Ultrasound synergized with three-phase partitioning for extraction and separation of Corbicula fluminea polysaccharides and possible relevant mechanisms. Ultrasonic Sonochemistry, 40, 128-134. (SCI, JCR声学一区,IF4.22TOP期刊).

2017

1. Yan, J.K*., Wang, Y.Y., Qiu, W.Y., Ma, H., Wang, Z.B., & Wu, J.Y. (2017). Three-phase partitioning as an elegant and versatile platform applied to non-chromatographic bioseparation process. Critical Reviews in Food Science and Nutrition. DOI:10.1080/10408398.2017.1327418. (SCI, JCR一区, IF 6.08Top期刊).

2. Yan, J.K*, Wang, Y.Y., Qiu, W.Y., Wu, L.X., Ding, Z.C., Cai, W.D. (2017). Purification, structural characterization and bioactivity evaluation of a novel proteoglycan produced by Corbicula fluminea. Carbohydrate Polymers, 176, 11-18. (SCI, JCR应用化学一区IF:4.81TOP期刊).

3. Yan, J.K*, Qiu, W.Y., Wang, Y.Y., Wu, L.X., Cheung, P.C.K. (2017). Formation and characterization of polyelectrolyte complex synthesized by chitosan and carboxylic curdlan for 5-fluorouracil delivery. International Journal of Biological Macromolecules, (SCI, JCR二区,IF 3.67)

4. Qiu, W.Y., Wang, K., Wang, Y.Y., Ding, Z.C., Wu, L.X., Cai, W.D., Yan, J.K*. (2017). pH dependent green synthesis of gold nanoparticles by completely C6-carboxylated curdlan under high temperature and various pH conditions. International Journal of Biological Macromolecules, (SCI, JCR二区,IF 3.67)

5. Yan, J.K*., Qiu, W.Y., Wang, Y.Y., & Wu, J.Y. (2017). Biocompatible polyelectrolyte complex nanoparticles from lactoferrin and pectin as potential vehicles for antioxidative curcumin. Journal of Agricultural and Food Chemistry, 65(28), 5720-5730. (SCI, JCR一区,IF 3.15, TOP期刊).

6. Yan, J.K*., Wang, Y.Y., Qiu, W.Y., & Wu, J.Y. (2017). Construction and characterization of nanosized curdlan sulfate/chitosan polyelectrolyte complex toward drug release of zidovudine. Carbohydrate Polymers, 174, 209-216. (SCI, JCR应用化学一区IF:4.81TOP期刊).

7. Yan, J.K*., Pei, J.J., Ma, H.L., Wang, Z.B., & Liu, Y.S*. (2017) Advances in Antitumor Polysaccharides from Phellinus sensu lato: Production, Isolation, Structure, Antitumor Activity, and Mechanisms. Critical Reviews in Food Science and Nutrition. 57(6): 1256-1269. (SCI, JCR一区, IF 6.08Top期刊).

8. Yan, J.K*., Wang, Y.Y., Qiu, W.Y., Shao, N. (2017). Three-phase partitioning for efficient extraction and separation of polysaccharides from Corbicula fluminea. Carbohydrate Polymers, 163, 10-19. (SCI, JCR应用化学一区,IF:4.81TOP期刊).

9. Wang, Y.Y., Qiu, W.Y., Wang, Z.B., Ma, H.L., Yan, J.K*. (2017). Extraction and characterization of anti-oxidative polysaccharide–protein complexes from Corbicula fluminea through three-phase partitioning. RSC Advances, 7, 11067-11075. (SCI, JCR二区SCI, 3.11).

2016

1. Yan, J.K*., Wang, Y.Y., Zhu, L., & Wu, J.Y*. (2016) Green synthesis and characterization of zinc oxide nanoparticles using carboxylic curdlan and their interaction with bovine serum albumin. RSC Advances, 6, 77752-77759 (SCI, JCR二区SCI, 3.11)

2. Wang, Z.B., Chen, B.B., Luo, L., & Yan, J.K*. (2016) Fractionation, physicochemical characteristics and biological activities of polysaccharides from Pueraria lobata roots. Journal of the Taiwan Institute of Chemical Engineers, 67 54-60. (SCI, JCR二区,IF 4.22)

3. Yan, J.K*., Wang, Y.Y., Wang, Z.B., Ma, H.L., Pei, J.J. (2016). Structural characteristics and antioxidant activity in vivo of a polysaccharide isolated from Phellinus linteus mycelia. Journal of the Taiwan Institute of Chemical Engineers, 65, 110-117. (SCI, JCR二区,IF 4.22)

4. Yan, J.K*., Wang, Y.Y., Wang, Z.B., Ma, H.L., Pei, J.J., & Wu, J.Y*. (2016). Structure and antioxidative property of a polysaccharide from an ammonium oxalate extract of Phellinus linteus. International Journal of Biological Macromolecules, 9, 92-99. (SCI, JCR二区,IF 3.67)

5. Yan, J.K*., Wang, Y.Y., Wang, Z.B., Ma, H.L. (2016). Ultrasonic effects on the degradation kinetics, preliminary characterization and antioxidant activities of polysaccharides from Phellinus linteus mycelia. Ultrasonics Sonochemistry, 29, 251-257. (SCI, JCR声学一区,IF4.22TOP期刊).

6. Chen, X., Yan, J.K., Wu, J.Y*. (2016). Characterization and antibacterial activity of silver nanoparticles prepared with a fungal exopolysaccharide in water. Food Hydrocolloids. 53, 69-74. (SCI, JCR一区,IF:4.75TOP期刊).

7. Zhang, H.N., Ma, Hai-Le, Zhou, C.S., Yang, Y., Yin, X.L., & Yan, J.K*. (2016). Enhanced production and antioxidant activity of endo-polysaccharides from Phellinus igniarius mutants screened by low power He-Ne laser and ultraviolet induction. Bioactive Carbohydrates and Dietary Fibre, http://dx.doi.org/10.1016/j.bcdf.2016.11.006.

2015

1. Yan, J.K*., Pei, J.J., Ma, H.L., Wang, Z.B. (2015). Effects of ultrasound on molecular properties, structure, chain conformation and degradation kinetics of carboxylic curdlan. Carbohydrate Polymers. 121,64-70. (SCI, JCR应用化学一区,IF:4.81TOP期刊).

2. Yan, J.K*., Liu J.L., Sun, Y.J., Tang, S., Mo, Z.Y., & Liu, Y.S.* (2015). Green synthesis of biocompatible carboxylic curdlan-capped gold nanoparticles and its interaction with protein. Carbohydrate Polymers.117,771-777. (SCI, JCR应用化学一区,IF:4.81TOP期刊).

3. Yan, J.K*., Ma, H.L., Chen, X., Pei, J.J., Wang, Z.B., Wu, J.Y.* (2015). Self-aggregated nanoparticles of carboxylic curdlan-deoxycholic acid conjugates as a carrier of doxorubicin. International Journal of Biological Macromolecules, 72, 333-340 (SCI, JCR二区,IF: 3.67).

4. Yan, J.K*., Ma, H.L., Cai, P.F., Wu, J.Y.* (2015). Highly selective and sensitive nucleic acid detection based on polysaccharide-functionalized silver nanoparticles. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 134, 17-21. (SCI, JCR二区,IF:2.54).

5. Pei, J.J., Wang, Z.B., Ma, H.L., Yan, J.K*. (2015). Structural features and antitumor activity of a novel polysaccharide from alkaline extract of Phellinus linteus mycelia. Carbohydrate Polymers, 115, 472-477 (SCI, JCR应用化学一区,IF:4.81TOP期刊)

6. Yan, J.K*., Wang, Y.Y., Ma, H.L. (2015). Green synthesis and stabilization of gold nanoparticles via carboxymethylated curdlan. Current Topics in Nutraceutical Research, 13(4):259-266 (SCIJCR四区).

7. Yan, J.K.*, Wang, Y.Y. (2015). Random-centroid optimization of ultrasound- -assisted extraction of polysaccharides from Cordyceps sinensis mycelium. Current Topics in Nutraceutical Research, 13(4):167-172 (SCIJCR四区).

2014

1. Yan, J.K*., & Wu, J.Y. (2014). Submerged Fermentation of Medicinal Fungus Cordyceps sinensis for Production of Biologically Active Mycelial Biomass and Exopolysaccharides. Production of Biomass and Bioactive Compounds Using Bioreactor Technology, Springer, pp. 93-120 (Book Chapter).

2. Zhang, H.N., Ma, H.L.,* Liu, W., Pei, J.J., Wang, Z.B., Zhou, H.J., Yan, J.K*. (2014). Ultrasound enhanced production and antioxidant activity of polysaccharides from mycelial fermentation of Phellinus igniarius. Carbohydrate Polymers, 113, 380-387. (SCI, JCR应用化学一区,IF:4.81TOP期刊)

3. Yan, J.K*., Ma, H.L., Pei, J.J., Wang, Z.B., Wu, J.Y.* (2014). Facile and effective separation of polysacchrides and proteins from Cordyceps sinensis mycelia by ionic liquid aqueous two-phase system. Separation and Purification Technology,135, 278-284. (SCI, JCR二区,IF:3.36).

4. Wang, Z.B., Pei, J.J., Ma, H.L., Cai, P.F., Yan, J.K.* (2014). Effect of extraction media on preliminary characterizations and antioxidant activities of Phellinus linteus polysaccharides. Carbohydrate Polymers, 109: 49-55. (SCI, JCR应用化学一区,IF:4.81TOP期刊)

5. Yan, J. K.,* Wang, W.Q., & Wu, J.Y.* (2014). Recent advances in Cordyceps sinensis polysaccharides: mycelial fermentation, isolation, structure, and bioactivities: a review. Journal of Functional Foods, 6, 33-47. (SCI, JCR一区IF:3.14, TOP期刊,ESI高被引论文,被引42)

6. Yan, J.K.*, Ma, H.L., Cai, P.F., Zhang, Q., Hu, N.Z., Feng, X.B., Wu, J.Y.* (2014) Structural characteristics and antioxidant activities of different families of 4-acetamido-TEMPO-oxidized curdlan. Food Chemistry, 143, 530-535. ((SCI, JCR食品科技一区IF:4.53TOP期刊)

2013

1. Yan, J.K.*, Cai P.F., Cao, X.Q., Ma, H.L., Zhang, Q., Hu, N.Z., Zhao, Y.Z. (2013). Green synthesis of silver nanoparticles using 4-acetamido-TEMPO-oxidized curdlan. Carbohtdrate Polymers, 97, 391-397. (SCI, JCR应用化学一区,IF:4.81TOP期刊)

2. Yan, J.K.*, Cai, P.F., Cao, X.Q., Fan, T.T., Ma, H.L. (2013). Studies on interaction of polysaccharide-templated silver nanoparticles with bovine serum albumin. Journal of Inorganic and Organometallic Polymers and Materials, 23, 1383-1388. (SCI, JCR四区,IF:1.58)

3. Yan, J. K., Wang, W.Q., Ma, H.L., & Wu, J.Y.* (2013). Sulfation and enhanced antioxidant capacity of an exopolysaccharide produced by the medicinal fungus Cordyceps sinensis. Molecules, 18(1), 167-177. (SCI, JCR三区,IF:2.86)

2012年及以前

1. Yan, J. K., Wang, W.Q., Li, L., & Wu, J.Y.* (2011). Physiochemical properties and antitumor activities of two α-glucans isolated from hot water and alkaline extracts of Cordyceps (Cs-HK1) fungal mycelia, Carbohydrate Polymers, 85, 753-758. (SCI, JCR应用化学一区,IF:4.81TOP期刊)

2. Yan, J. K., Li, L., Wang, Z. M., & Wu, J.Y.* (2010).Structural elucidation of an exopolysaccharide from mycelial fermentation of a Tolypocladium sp. fungus isolated from wild Cordyceps sinensis, Carbohydrate Polymers, 79(1), 125-130. (SCI, JCR应用化学一区,IF:4.81TOP期刊)

3. Yan, J. K., Li, L., Wang, Z. M.,Leung, P. H., Wang,W. Q., & Wu, J.Y.* (2009). Acidic degradation and enhanced antioxidant activities of exopolysaccharides from Cordyceps sinensis mycelial culture, Food Chemistry, 117(4), 641-646. (SCI, JCR食品科技一区,IF:4.53TOP期刊)


【科研项目】

在研项目

1. 国家自然科学基金-面上项目:超声场微环境中果胶溶液构象的转变规律、机理及与功能性质的构效关系(31671812), 2017.01-2020.12,主持,在研。

2. 江苏省现代农业重点研发面上项目:麦麸可溶性膳食纤维绿色高效制备关键技术研究与应用(BE2017362),50万元,2017.7-2019.6,技术主持,在研。

3. 江苏省自然科学基金-青年基金项目:桑黄活性多糖抗肿瘤作用的肠道黏膜免疫机制研究(BK20140542),2014.7-2017.6,主持,在研。

4. 南昌大学食品科学与技术国家重点实验室开放基金:桑黄多糖调节肠粘膜γδT细胞免疫的抗肿瘤作用及机理研究(SKLF-KF-201611),2016.5 -2018.4,主持,在研。

结题项目

1. 中国博士后科学基金面上项目:可德兰硫酸酯溶液构象与抗HIV-1活性的构效关系(2013M531292),2013.7-2015.6,主持,已结题。

2. 江苏大学高级人才基金资助项目:新型药用虫草胞外多糖结构表征、修饰及抗氧化构效关系(105DG129),2010.10-2013.10,主持,已结题。

3. 江南大学糖化学与生物技术教育部重点实验室开放基金项目:微波辅助多糖基银纳米粒子合成及其抗HIV-1活性的构效关系(KLCCB-KF201203),2012.12-2014.12,主持,已结题。

4. 江苏省农产品物理加工重点实验室开放基金项目:逆流循环超声辅助桑黄多糖的制备与抗肿瘤血管生成构效关系的研究(JAPP2010-7),2012.5-2014.5,主持,已结题。

5. 农业部公益性行业科研专项-子课题:长江流域等三区域稻谷储藏技术设施研究与示范(201003077),2010.12-2014.12,第二负责人,已结题。

6. 国家自然科学基金-面上项目:蛋白质扫频超声预处理促进其酶解反应的机理及控制机制研究(31071502),2011.1-2013.12,排名第四,已结题。

7. 江苏省科技支撑计划(农业部分)项目:麦胚降血压肽制备关键技术的放大及麦胚多肽香醋的开发研究(BE2010384),2011.7-2013.7,排名第三,已结题。


【科研成果及奖励】

教学获奖:

2012年江苏大学第六届教师教学竞赛新教师组优秀奖。


【所获专利】

目前申请发明专利10余项,授权7项:

1. 发明专利:一种多糖基银纳米粒子的制备方法. ZL 201310435968.2

2. 发明专利:一种虫草菌丝体多糖分离纯化的方法. ZL 201310434343.4

3. 发明专利:一种脱氧胆酸基-氧化可德兰多糖纳米粒子及制备方法. ZL 201310467173.X

4. 发明专利:一种香菇多糖快速分离的方法. ZL 201310467100.0

5. 发明专利:一种多糖衍生物诱导的金纳米粒子的可控制备方法. ZL 201510332688.8

6. 发明专利:一种利用胆碱离子液双水相体系分离多糖和蛋白质的方法. ZL 201510296253.2

7. 发明专利:一种用于糙米脂肪酶酶活稳定和食用品质改善的处理方法. 授权号:2015032510063532


【在读硕、博士人数】

硕士研究生5


【已毕业硕、博士人数】


【指导本科生人数】

21


【以上资料更新日期】:

2017.09.12

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